Influence of Obesity on Coronary Artery Disease and Clinical Outcomes in the ADVANCE Registry.

Document Type

Article

Publication Date

5-2023

Publication Title

Circ Cardiovasc Imaging

Abstract

BACKGROUND: The relationship between body size and cardiovascular events is complex. This study utilized the ADVANCE (Assessing Diagnostic Value of Noninvasive FFR

METHODS: The ADVANCE registry enrolled patients undergoing evaluation for clinically suspected CAD who had >30% stenosis on cardiac computed tomography angiography. Patients were stratified by BMI: normal/m

RESULTS: Among 5014 patients, 2166 (43.2%) had a normal BMI, 1883 (37.6%) were overweight, and 965 (19.2%) were obese. Patients with obesity were younger and more likely to have comorbidities, including diabetes and hypertension (all

CONCLUSIONS: Patients with obesity in the ADVANCE registry were less likely to have anatomically obstructive CAD by cardiac computed tomography angiography but had a similar degree of physiologically significant CAD by FFR

Volume

16

Issue

5

First Page

014850

Last Page

014850

DOI

10.1161/CIRCIMAGING.122.014850

ISSN

1942-0080

PubMed ID

37192296

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