Title
Prospective Multicenter Comparison of Open and Robotic Radical Prostatectomy: The PROST-QA/RP2 Consortium.
Document Type
Article
Publication Date
1-26-2022
Publication Title
Journal of Urology
Abstract
PURPOSE: To evaluate the comparative effectiveness of robot-assisted laparoscopic prostatectomy (RALP) and open radical prostatectomy (ORP) in a multicenter study.
MATERIALS AND METHODS: We evaluated men with localized prostate cancer at eleven high-volume academic medical centers in the United States from the PROST-QA (2003-2006) and the PROST-QA/RP2 cohorts (2010-2013) with a pre-specified goal of comparing RALP (N=549) and ORP (N=545). We measured longitudinal patient-reported health related quality of life (HRQOL) at pre-treatment, 2, 6, 12, and 24 months, and pathologic and peri-operative outcomes/complications.
RESULTS: Demographics, cancer characteristics, and margin status were similar between surgical approaches. ORP subjects were more likely to undergo lymphadenectomy (89% vs 47%; p
CONCLUSIONS: In high-volume academic centers, RALP and ORP patients may expect similar long-term HRQOL outcomes. Overall, RALP patients have less pain, shorter hospital stays, and fewer post-surgical complications such as blood transfusions, infections, DVTs, and bladder neck contractures.
TRIAL REGISTRATION: NCT01325506: Effectiveness of Open and Robotic Prostatectomy (PROSTQA- RP2).
Volume
207
Issue
1
First Page
127
Last Page
136
Recommended Citation
Chang P, Wagner AA, Regan MM, Smith JA, Saigal CS, Litwin MS, et al [Wood DP] Prospective multicenter comparison of open and robotic radical prostatectomy: the prost-qa/rp2 consortium. J Urol. 2022 Jan;207(1):127-136. doi: 10.1097/JU.0000000000002176. PMID: 34433304
DOI
10.1097/JU.0000000000002176
PubMed ID
34433304