787914 - National Trends and Survival Outcomes of Performing Immediate Breast Reconstruction for Male Breast Cancer Patients: Propensity Scoring Analysis

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Annals of Surgical Oncology


Background/Objective: There is a lack of data on the trends of performing immediate breast reconstruction (IBR) in male breast cancer (MBC) patients following a mastectomy. The purpose of this study is to examine the national trends and outcomes of performing IBR in MBC patients following a mastectomy. Methods: The National Cancer Database (NCDB) registry from 2004 to 2014 was used to identify non-metastatic MBC patients who had a mastectomy with or without an IBR. Patients’ demographics, readmission, and long-term overall mortality (OM) were compared between IBR and no-IBR patients. Univariate, multivariate, and propensity score weighted analyses were used to compare study groups and outcomes. Results: A total of 370 (3.35%) IBR and 10,677 (96.65%) no-IBR patients were identified. Median follow-up was 59.63 months. Compared to no-IBR patients, IBR patients were more likely to be younger (Mean: 52, SD: 11.7 vs. Mean: 65.8, SD: 12.8), be Hispanic, live in a metropolitan county, and have private insurance, less comorbidities and higher income (p<0.05). Rates of IBR increased significantly from 1.56% in 2004 to 4.15% in 2014 (p<0.05). IBR types were 130 (35%) tissue-based, 96 (26%) implant-based, 42 (11%) combined tissue/implant, and 102 (28%) were non-specified. IBR was not associated with 30-day readmission or 90-day mortality. In the adjusted propensity score weighted analysis, IBR was not associated with OM for Stage I (HR:0.45, p=0.23), Stage II (HR:0.95, p=0.92), or Stage III (HR:1.48, p=34) Conclusions: Our data suggest that IBR in MBC patients has been increasing over the years, with the tissue-based IBR as the most common type. There was no association between IBR and 30-day readmission rates or OM when compared to MBC patients who did not receive an IBR.




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