Annals of Surgical Oncology
Background/Objective: Current National Comprehensive Cancer Network (NCCN) guidelines recommend modified radical mastectomy (MRM) as the surgical treatment of choice for nonmetastatic inflammatory breast cancer (IBC). Using data from the National Cancer Database (NCDB), our study compared the national trends and outcomes of breast-conserving surgery (BCS) vs. MRM for the treatment of IBC. Methods: NCDB data from 2004 to 2014 were retrospectively analyzed. Patients’ demographics, tumor characteristics, and overall mortality (OM) trends were compared between BCS and MRM cases of IBC. Univariate, multivariate, and propensity score weighted analyses were done to compare study groups and build a predictive model for undergoing BCS. Results: A total of 445 (4.01%) BCS and 10,645 (95.99%) MRM cases were identified. Median follow-up was 58.48 months. Compared to MRM, BCS patients were more likely to be older (Mean:61, SD:15.4 vs. Mean:56, SD:12.9- p
Sebai M, Karabon P, Lee D, Sayee K, Dekhne N. Trends, survival outcomes, and predictors of non-adherence to mastectomy guidelines for non-metastatic inflammatory breast cancer: Stage-stratified propensity scoring analysis of NCDB. Annals of Surgical Oncology, 2020 May 27(Suppl 2,2 SI):S633-S634.