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  Advanced Particle Therapy Delivery

  Peyman Kabolizadeh, Xuanfeng Ding, and Xiaoqiang Li

  Publication Date: 5-2022

  Topics covered include:

  • Background information related to particle therapy, including the clinically relevant physics, radiobiological, and practical aspects of developing a particle therapy program
  • “Niche” treatments, such as FLASH, BNCT, and GRID therapy
  • The simulation process, target volume delineation, and unique treatment planning considerations for each disease site
  • Less commonly used ions, such as fast neutrons or helium

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  Trigeminal Neuralgia

  Peter Y. Chen

  Publication Date: 7-28-2018

  Trigeminal neuralgia (TN) is a pain syndrome typified by paroxysms of intense stabbing, electric shock-like unilateral facial pain provoked by light touch in the distribution of the fifth cranial or trigeminal nerve. Also known as tic douloureux to describe the involuntary facial movement or contortions of the facial features in reaction to the severity/intensity of the pain, the cause is usually idiopathic, but secondary causes such as vascular anomalies, tumors, or multiple sclerosis may be identified by neuroimaging. Antiepileptic drug therapy provides initial pain relief in the majority of patients. However, the TN pain may become refractory to pharmacological agents leading to referrals for evaluation of surgical or irradiation management ranging from operative craniotomy to radiation-based radiosurgical approaches. This chapter will highlight the key features of TN and elucidate state-of-the-art medicinal, surgical and radiotherapeutic regimens in the treatment of TN based on retrospective, observational clinical investigations along with systemic and comparative reviews.

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  Neuroradiology: Spectrum and Evolution of Disease

  Daniel L. Noujaim

  Publication Date: 10-29-2018

  Kummel disease was first described by Hermann Kummell in 1891 as delayed posttraumatic vertebral collapse occurring weeks or months after an often minimal injury. The mechanism is still debated. These lesions are most widely believed to be secondary to delayed osteonecrosis of the vertebral body, potentially related to vascular disruption of the anterior watershed territory of the vertebral body following trauma. It is a rarely reported entity, which likely occurs more frequently than recognized.

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  Neuroradiology: Spectrum and Evolution of Disease

  Juan Small, Daniel Noujaim, Daniel Thomas Ginat, Hillary R. Kelly, and Pamela W. Schaefer

  Publication Date: 10-29-2018

  Acquire a better understanding of disease evolution and treatment response with Neuroradiology Spectrum and Evolution of Disease. The unique format includes carefully chosen clinical images that depict the pathologic evolution of disease from initial presentation across the continuum of progression. Colorful graphics plot characteristic changes, helping you visualize how normal and abnormal variations alter over time. Extensive illustrations and concise descriptions distill complex concepts, making this first-of-its-kind resource an excellent tool for imaging interpretation and clinical problem solving.