Title

Rectal cancer in young patients: incidence and outcome disparities.

Document Type

Article

Publication Date

10-1-2020

Publication Title

Journal of Gastrointestinal Oncology

Abstract

Background: There is an alarming rise in incidence among young patients with rectal cancer. The National Cancer Database (NCDB) and Surveillance, Epidemiology, and End Results Analysis (SEER) databases may help identify population level disparities in incidence and cancer-related outcomes.

Methods: A total of 197,178 patients within the SEER 18 registry and 221,886 patients from the NCDB database with rectal cancer were evaluated in this retrospective cohort study. The analyzed cohort consisted of young (

Results: A total of 6,144 young patients were identified from the SEER 18 registry and a total of 17,819 young patients were identified from the NCDB. From 1990 to 2016, there was a significant change in rectal cancer incidence, with a steadily increasing APC of 3.06 (P

Conclusions: The current study adds to the growing body of literature demonstrating an alarming increase in incidence of rectal cancer among young patients. Moreover, the incidence appears to be increasing particularly among young white patients and driven by stage III disease.

Volume

11

Issue

5

First Page

880

Last Page

893

DOI

10.21037/jgo-20-197

ISSN

2078-6891

PubMed ID

33209484

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