Characterizing spatial differences between SPECT-ventilation and SPECT-perfusion in patients with lung cancer undergoing radiotherapy.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
This study investigates agreement between ventilation and perfusion for lung cancer patients undergoing radiotherapy. Ventilation-perfusion scans of nineteen patients with stage III lung cancer from a prospective protocol were compared using voxel-wise Spearman correlation-coefficients. The presented results show in about 25% of patients, ventilation and perfusion exhibit lower agreement.
Forghani F, Patton T, Kwak J, Thomas D, Diot Q, Rusthoven C, Castillo R, Castillo E, Grills I, Guerrero T, Miften M, Vinogradskiy Y. Characterizing spatial differences between SPECT-ventilation and SPECT-perfusion in patients with lung cancer undergoing radiotherapy. Radiother Oncol. 2021 Jul;160:120-124. doi: 10.1016/j.radonc.2021.04.022. Epub 2021 May 6. PMID: 33964328; PMCID: PMC8489737.