[18 F]FDG cardiac PET imaging in a canine model of radiation-induced cardiovascular disease associated with breast cancer radiotherapy
American journal of physiology. Heart and circulatory physiology
Radiotherapy for the treatment of left-sided breast cancer increases the long-term risk of cardiovascular disease. The purpose of the present study was to noninvasively image the progression of radiation-induced cardiac inflammation in a large animal model using a hybrid PET and MRI system. Five canines were imaged using [
El-Sherif O, Xhaferllari I, Sykes J, Butler J, deKemp RA, Renaud J, Yin H, Wilk B, Sullivan R, Pickering JG, Battista J, Wisenberg G, Prato FS, Gaede S. [18F]FDG cardiac PET imaging in a canine model of radiation-induced cardiovascular disease associated with breast cancer radiotherapy. Am J Physiol Heart Circ Physiol. 2019 Mar 1;316(3):H586-H595. doi: 10.1152/ajpheart.00273.2018. Epub 2018 Dec 21. PMID: 30575441.