Title

Diphenhydramine Toxicity

Authors

David A. Huynh, Beaumont Health Resident
Malak Abbas, Beaumont Health
Ali Dabaja, Beaumont Health

Document Type

Article

Publication Date

5-8-2022

Publication Title

StatPearls [Internet]

Abstract

Diphenhydramine is a first-generation antihistamine with anticholinergic and sedative properties. It is most commonly used for the treatment of nausea, vomiting, allergic rhinitis, mild to severe allergic reactions (e.g., anaphylaxis), and as a mild sleep aid. While used for a wide array of medical indications, diphenhydramine is also one of the most commonly abused medications in the United States (U.S.). Acute intoxications of diphenhydramine can have severe, potentially fatal consequences if not managed appropriately in a timely manner.

Recommended Citation

Huynh DA, Abbas M, Dabaja A. Diphenhydramine toxicity. 2022 May 8. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan–. PMID: 32491510.

PubMed ID

32491510