Cutaneous and Superficial Soft Tissue CD34+ Spindle Cell Proliferation
Archives of pathology & laboratory medicine
CONTEXT: - Cutaneous and superficial soft tissue spindle cell proliferations with CD34 expression represent a unique heterogeneous group of lesions. They can pose diagnostic challenges for unaware pathologists in their daily practice.
OBJECTIVE: - To review selected entities of CD34
DATA SOURCES: - All information used in the article is obtained from published literature by PubMed search and Internet-based search engines. The authors' collective experience and real-life examples are also used.
CONCLUSIONS: - Spindle cell proliferations with CD34 positivity can be worked up to a definitive diagnosis by using clinical, histopathologic, and immunophenotypical findings. Familiarity with these entities helps pathologists make the accurate diagnosis.
Yang H, Yu L. Cutaneous and Superficial Soft Tissue CD34+ Spindle Cell Proliferation. Arch Pathol Lab Med. 2017 Aug;141(8):1092-1100. doi: 10.5858/arpa.2016-0598-RA. Epub 2017 Jun 22. PMID: 28639855.