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Introduction Rare cases of primary neuroendocrine carcinomas (NEC) have been reported in some head and neck structures such as the lingual tonsil, larynx, and major salivary glands.1 However, we report a primary large cell neuroendocrine carcinoma of the tonsillar fossa which has not been previously reported. The World Health Organization (WHO) classifies large cell neuroendocrine carcinoma (LCNEC) as a high-grade, poorly differentiated tumor, with >20 mitotic counts per high power field (HPF) and a Ki-67 index of >20%
Sims J, Belavek T, Korkigian S. Primary large cell neuroendocrine carcinoma of left tonsillar fossa: a Case report. Poster presented at Beaumont Hospital Farmington Hills 2022 Alvin Yarrows Research Day; 2022 May; Farmington Hills, MI.