Pre-existing Vestibular Symptoms Are Associated With Acute Vestibular Symptoms After Gamma Knife Therapy for Vestibular Schwannoma.

Authors

Dennis I. Bojrab 2nd, Beaumont Health Resident
Christian G. Fritz, Oakland University William Beaumont School of Medicine Student
Christopher A. Schutt, Beaumont Health
Robert S. Hong, Beaumont Health
Peter Y Chen, Beaumont Health
Ann Maitz, Beaumont Health
Dennis I. Bojrab, Beaumont Health
Kenny F. Linn

Document Type

Article

Publication Date

7-1-2021

Publication Title

Otology & Neurotology

Abstract

OBJECTIVE: To identify pretreatment variables associated with the development of acute vestibular symptoms after Gamma Knife (GK) treatment for Vestibular Schwannoma (VS).

STUDY DESIGN: Retrospective case series.

SETTING: Tertiary neurotology referral center.

PATIENTS: Patients treated with GK radiosurgery for VS between March 2007 and March 2017 were considered for this study. Patients with neurofibromatosis type II, previous VS surgery, follow-up less than 6 months, or the lack of T2 magnetic resonance imaging (MRI) sequences from the day of treatment were excluded.

MAIN OUTCOME MEASURES: The presence of acute vestibular symptoms arising within 6 months after GK was the main outcome variable. Tumor, patient, and treatment characteristics were gathered from the medical record.

RESULTS: In total, 98 patients met inclusion criteria. The incidence of acute vestibular symptoms occurring within 6 months after GK treatment was 46.9%. Post-GK vestibular symptoms were reported at a significantly higher frequency among subjects who had reported vestibular symptoms before their treatment (p = 0.001). Tumor size was not associated with a propensity to develop acute vestibular symptoms (p = 0.397). The likelihood of receiving a referral to vestibular rehabilitation services was not significantly different among patients with larger versus smaller tumor size, as defined by 1.6 cm and 1.4 cm thresholds (p = 0.896, p = 0.654).

CONCLUSIONS: Inquiries aimed at revealing a history of vestibular complaints may prove useful in counseling patients on the likelihood of experiencing acute vestibular symptoms after treatment of Vestibular Schwannoma with Gamma Knife therapy.

Volume

42

Issue

6

First Page

912

Last Page

917

Recommended Citation

Bojrab DI 2nd, Fritz CG, Lin KF, Schutt CA, Hong RS, Babu SC, Chen PY, Maitz A, Bojrab DI. Pre-existing Vestibular Symptoms Are Associated With Acute Vestibular Symptoms After Gamma Knife Therapy for Vestibular Schwannoma. Otol Neurotol. 2021 Jul 1;42(6):912-917. doi: 10.1097/MAO.0000000000003064. PMID: 33591068.

DOI

10.1097/MAO.0000000000003064

ISSN

1537-4505

PubMed ID

33591068