Acute, post-injury peripheral blood mobilization therapy with a CXCR4 antagonist improved bone tunnel healing and graft integration following ACL reconstruction surgery in a rat model.
Baker KC, Hartner S, Fleischer MM, Newton MD, Acker WB, Altman P, Bush C, Maerz T, Bedi A. Modulation of the acute post-anterior cruciate ligament rupture intra-articular environment via recruitment of marrow-derived stem cells to promote bone tunnel healing in ACL reconstruction. Poster presented at: American Academy of Orthopaedic Surgeons. 2021 Annual Meeting. 2021 Aug 29- Sep 3; San Diego, CA.