Surface Modification Techniques to Enhance Osseointegration of Spinal Implants

Document Type

Article

Publication Date

11-15-2020

Publication Title

The Journal of the American Academy of Orthopaedic Surgeons

Abstract

Biomechanical function, specifically implantation technique and immediate surgical fixation, of orthopaedic implants is the primary consideration during the development of orthopaedic implants. Biologic and material characteristics are additional factors to include in the design process because of the direct impact on short- and long-term implant performance. The body's initial interaction with implant materials can affect protein- and cell-based function, thereby either promoting or impeding osseointegration. An understanding and inclusion of the biologic response, material surface morphology, and material surface chemistry in implant design is crucial because these factors ultimately determine implant function and patient outcomes. Highlighting the biologic- and material-related advantages and inadequacies of current and potential implant materials as well as applications may guide further research and development of implant materials and designs.

Volume

28

Issue

22

First Page

e988

Last Page

e994

DOI

10.5435/JAAOS-D-17-00645

PubMed ID

32868701

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