Targeted Metabolic Profiling of Post-Mortem Brain from Infants Who Died from Sudden Infant Death Syndrome.
Currently little is known about the underlying pathophysiology associated with SIDS, and no objective biomarkers exist for the accurate identification of those at greatest risk of dying from SIDS. Using targeted metabolomics, we aim to profile the medulla oblongata of infants who have died from SIDS (n = 16) and directly compare their biochemical profile with age matched controls. Combining data acquired using
Graham SF, Turkoglu O, Kumar P, Yilmaz A, Bjorndahl TC, Han B, Mandal R, Wishart DS, Bahado-Singh RO. Targeted Metabolic Profiling of Post-Mortem Brain from Infants Who Died from Sudden Infant Death Syndrome. J Proteome Res. 2017 Jul 7;16(7):2587-2596. doi: 10.1021/acs.jproteome.7b00157. Epub 2017 Jun 20. PubMed PMID: 28608686.