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Description

Subacute combined degeneration (SCD) of the spinal cord is a disease involving the lateral and posterior columns of the spinal cord that can manifest in patients with vitamin B12 deficiency.

• Nitrous oxide (N2O) induced SCD of the spinal cord is a result of N2O interfering with the metabolism of vitamin B12 and results in nervous system demyelination

• This is an infrequent complication of N2O anesthesia however cases are rising with recreational N2O use.

• Given wide availability of N2O, clinicians must maintain a high index of suspicion when confronting patients with concerning clinical pictures.

Publication Date

5-4-2023

Disciplines

Internal Medicine | Orthopedics

Comments

2023 Alvin Yarrows Research Day at Beaumont Hospital Farmington Hills, Farmington Hills, MI, May 4, 2023.

Subacute Combined Degeneration of the Spinal Cord Induced by Nitrous  Oxide Abuse: A Rare Patient Presentation to a Spine Surgery Clinic

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