Demographics and Survival in Malignant Pleural Mesothelioma: Analysis of Seer Data

Document Type

Conference Proceeding

Publication Date


Publication Title

Journal of Thoracic Oncology


Background: Mesothelioma is an uncommon malignancy arising in 80% of cases from the mesothelial lining of the pleura. Less frequently it can originate in the peritoneum, pericardium or the tunica vaginalis. Prognosis remains extremely poor even with treatment and data regarding the demographics and survival of mesothelioma is poorly described owing to its rarity. Method: Using ICD-O-3 histology code 9050 in the Surveillance Epidemiology and End Results database (SEER), demographics and survival data on malignant pleural mesothelioma (MPM) diagnosed between 2005 and 2015 were abstracted. JMP 14 statistical software was used for data analysis. The SEER database does not record specific age above 85 years; for this reason, 872 cases were excluded. Results: A total of 3709 cases of MPM were identified. Most were Caucasian (3336, 90%) and male (2787, 75%); the average age was 70 ± 11 years. Overall, 1574 patients (42%) received chemotherapy. Median 10-year survival was 8 months (95% CI 8 to 9 months). Patients who received chemotherapy had improved survival (11 months, 95% CI 11 to 12 months) compared to those who did not (5 months, 95% CI 5 to 6 months, p




11, Supplement 1

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The International association for the Study of Lung Cancer (IASLC). North America Conference on Lung Cancer (NACLC), Chicago IL, October 2019.

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