Increasing Inpatient Mortality of Gastrointestinal Angiodysplasia With Bleeding in the United States: National Inpatient Sample, 2016 to 2020

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Conference Proceeding

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American Journal of the Medical Sciences


Purpose of Study: Gastrointestinal angiodysplasia (GIAD) are inherited or acquired aberrant blood vessels in the gastrointestinal (GI) tract. GIAD is an important cause of GI bleeding (GIB), especially in older population. The prevalence is unknown; however, it increases with age, and in patients with certain predisposing conditions, including end-stage renal disease (ESRD), von Willebrand disease (WV disease), aortic stenosis, and the presence of left ventricular assistive devices (LVADs). Previous studies have shown GIAD association with increased inpatient mortality. There are no recent studies showing inpatient outcomes of GIAD presenting with GIB. The purpose of this study is to highlight a recent increase in inpatient mortality from GIAD. Methods Used: We used National Inpatient Sample (NIS) databases from 2016–2020, and the International Classification of Diseases (ICD) 10 codes (K31811, K5521) to identify the population of interest. We included patients admitted with GIB secondary to GIAD who were >40 years old, and had non-elective admissions. We excluded hospitalizations secondary to other causes of variceal or non-variceal GIB. Outcomes of interest included inpatient mortality, length of stay (LOS), and inpatient cost. Summary of Results: Data analysis was done using STATA v17. Univariate and multivariate linear and logistic regression models were built based upon P value (P < 0.2) on univariate regression analysis to adjust for confounding variables. There is a decline in hospital admissions but an increase in inpatient mortality related to GIAD with GIB. Increasing age, hypovolemic shock, acute kidney injury, ESRD, atrial fibrillation, and chronic anticoagulation were associated with a statistically significant increase in mortality. The results are shown in tables.




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2023 Southern Regional Meetings (Society of General Internal Medicine, Southern Society For Pediatric Research, Academic Pediatric Association), February 2-4, 2023, New Orleans, LA.

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