In-Hospital Outcomes For Percutaneous Coronary Intervention In End-Stage Renal Disease Patients With Acute Coronary Syndrome
Journal of the Society for Cardiovascular Angiography & Interventions
In-hospital outcomes for percutaneous coronary interventions (PCI) in patients with end-stage renal disease (ESRD) presented with acute coronary syndrome (ACS) are unknown.
We included all patients with ACS treated with PCI using the NIS database. We calculated the odds ratio to compare in-hospital outcomes between the patients with ESRD vs. no ESRD.
We identified a total of 9,614,249 patients (9,343,527 without ESRD; 270,722 with ESRD). More females and non-caucasian people who underwent PCI had ESRD. The patients with ESRD also had increased comorbid conditions of diabetes, heart failure, peripheral arterial disease, and electrolyte abnormalities. PCI to treat ACS in ESRD patients was associated with higher in-hospital mortality (10.7% vs 3.6%, OR: 3.96; 95% CI 3.91-4.00), stroke (2.9% vs 1.7%, OR: 1.71; 95% CI 1.67-1.75), major bleeds (9.1% vs 5.7%, OR: 1.64; 95% CI 1.62-1.67), postprocedure bleeds (0.9% vs 0.6%, OR: 1.42; 95% CI 1.37-1.49), and vascular complications (1.3% vs 1.1%, OR: 1.16; 95% CI 1.31-1.20), p<0.0001 for all.
PCI in ESRD patients is associated with increased mortality, stroke and major bleeding due to increased comorbidities mainly peripheral vascular disease.
Dandu C, Chalek A, Zghouzi M, Ullah W, Razvi P, Osman H, et al. [Elmakshbr N, Alhusain R]. In-hospital outcomes for percutaneous coronary intervention in end-stage renal disease patients with acute coronary syndrome. J Soc Cardiovasc Angiogr Interv. 2022 May-Jun;1(Suppl 3):100064. doi:10.1016/j.jscai.2022.100064.