Therapeutic Anticoagulation Delays Death in COVID-19 Patients: Cross-Sectional Analysis of a Prospective Cohort.
A hypercoagulable state has been described in coronavirus disease 2019 (COVID-19) patients. Others have reported a survival advantage with prophylactic anticoagulation (pAC) and therapeutic anticoagulation (tAC), but these retrospective analyses have important limitations such as confounding by indication. We studied the impact of tAC and pAC compared with no anticoagulation (AC) on time to death in COVID-19. We performed a cross-sectional analysis of 127 deceased COVID-19 patients and compared time to death in those who received tAC (
Ionescu F, Grasso-Knight G, Castillo E, Naeem E, Petrescu I, Imam Z, Patel VK, Narasimhan M, Nair GB. Therapeutic Anticoagulation Delays Death in COVID-19 Patients: Cross-Sectional Analysis of a Prospective Cohort. TH Open. 2020 Sep 26;4(3):e263-e270. doi: 10.1055/s-0040-1716721. PMID: 32995704; PMCID: PMC7519875.