Pharmacokinetic and Pharmacodynamic Profiling of Minocycline for Injection following a Single Infusion in Critically Ill Adults in a Phase IV Open-Label Multicenter Study (ACUMIN).

Authors

Thomas P Lodise
Scott Van Wart
Zoe M Sund
Adam M Bressler
Akram Khan
Amy T Makley
Yasir Hamad
Robert A Salata
Fernanda P Silveira
Matthew D. Sims, Beaumont Health
Badih A Kabchi
Mohamed A Saad
Carrie Brown
Randolph E Oler
Vance Fowler
Richard G Wunderink

Document Type

Article

Publication Date

2-17-2021

Publication Title

Antimicrobial Agents and Chemotherapy

Abstract

Intravenous (i.v.) minocycline is increasingly used to treat infections caused by multidrug-resistant (MDR)

Volume

65

Issue

3

Recommended Citation

Lodise TP, Van Wart S, Sund ZM, Bressler AM, Khan A, Makley AT, Hamad Y, Salata RA, Silveira FP, Sims MD, Kabchi BA, Saad MA, Brown C, Oler RE Jr, Fowler V Jr, Wunderink RG. Pharmacokinetic and Pharmacodynamic Profiling of Minocycline for Injection following a Single Infusion in Critically Ill Adults in a Phase IV Open-Label Multicenter Study (ACUMIN). Antimicrob Agents Chemother. 2021 Feb 17;65(3):e01809-20. doi: 10.1128/AAC.01809-20. PMID: 33168615; PMCID: PMC8092545.

DOI

10.1128/AAC.01809-20

ISSN

1098-6596

PubMed ID

33168615