Emergency Visit Trends for Pediatric Anaphylaxis in Southeast Michigan.

Document Type

Conference Proceeding - Restricted Access

Publication Date


Publication Title

Annals of Emergency Medicine



Anaphylaxis is a serious allergic reaction that has the potential to be life-threatening if not recognized and managed rapidly. Several regional studies have shown increased incidence of anaphylaxis over the past decade. There are no published studies evaluating rates in southeast Michigan.

Study Objective

To determine rates of pediatric anaphylaxis in southeast Michigan between January 1, 2010 and December 31, 2019 and to describe the epidemiology of pediatric patients presenting to emergency centers in southeast Michigan with anaphylaxis.


We performed a retrospective chart review of all pediatric patients age 0-17 years old presenting to two large suburban emergency centers from 2010 to 2019 with a diagnosis of anaphylaxis using International Classification of Diseases, ninth and tenth revision, Clinical Modification codes. Epidemiological and visit data, including length of stay, use of intravenous medication and emergency severity index, were extracted and analyzed. Pediatric anaphylaxis rates were calculated based on detected anaphylaxis cases divided by total pediatric emergency department visits to the two emergency centers. A poisson regression model was used to predict rates of anaphylaxis per 100, 000 emergency department visits.


1,391 pediatric visits for anaphylaxis were identified during a period between January 1, 2010 and December 31, 2019. There was a significant rate of increase in pediatric anaphylaxis cases over the 10-year study period at both suburban emergency centers, with an annual increase of 21% and 14%. There was no significant change in trends in demographic factors. Most anaphylaxis cases were young, white males with private insurance. Most children did not receive intravenous medication (77%). Median length of stay increased by 1.5 hours over the study period and 92% of patients were discharged home.


Pediatric emergency center visits and length of stay for anaphylaxis have increased over the past 10 years in southeast Michigan.





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American College of Emergency Physicians Research Forum, Boston, MA, October 25-28, 2021.

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