Title
Utility of COVID-19 antigen testing in the emergency department.
Document Type
Article
Publication Date
1-15-2022
Publication Title
Journal of the American College of Emergency Physicians Open
Abstract
BACKGROUND: The BinaxNOW coronavirus disease 2019 (COVID-19) Ag Card test (Abbott Diagnostics Scarborough, Inc.) is a lateral flow immunochromatographic point-of-care test for the qualitative detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleocapsid protein antigen. It provides results from nasal swabs in 15 minutes. Our purpose was to determine its sensitivity and specificity for a COVID-19 diagnosis.
METHODS: Eligible patients had symptoms of COVID-19 or suspected exposure. After consent, 2 nasal swabs were collected; 1 was tested using the Abbott RealTime SARS-CoV-2 (ie, the gold standard polymerase chain reaction test) and the second run on the BinaxNOW point of care platform by emergency department staff.
RESULTS: From July 20 to October 28, 2020, 767 patients were enrolled, of which 735 had evaluable samples. Their mean (SD) age was 46.8 (16.6) years, and 422 (57.4%) were women. A total of 623 (84.8%) patients had COVID-19 symptoms, most commonly shortness of breath (
CONCLUSIONS: The BinaxNOW point-of-care test has good sensitivity and excellent specificity for the detection of COVID-19. We recommend using the BinasNOW for patients with symptoms up to 2 weeks.
Volume
3
Issue
1
First Page
12605
Last Page
12605
Recommended Citation
Peacock WF, Soto-Ruiz KM, House SL, Cannon CM, Headden G, Tiffany B, Motov S, Merchant-Borna K, Chang AM, Pearson C, Patterson BW, Jones AE, Miller J, Varon J, Bastani A, Clark C, Rafique Z, Kea B, Eppensteiner J, Williams JM, Mahler SA, Driver BE, Hendry P, Quackenbush E, Robinson D, Schrock JW, D'Etienne JP, Hogan CJ, Osborne A, Riviello R, Young S. Utility of COVID-19 antigen testing in the emergency department. J Am Coll Emerg Physicians Open. 2022 Jan 15;3(1):e12605. doi: 10.1002/emp2.12605. PMID: 35072154; PMCID: PMC8760952.
DOI
10.1002/emp2.12605
ISSN
2688-1152
PubMed ID
35072154