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Conference Proceeding - Restricted Access

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Publication Title

Journal of the American College of Cardiology


Background: Prosthetic valve type has been shown to affect conduction abnormalities following transcatheter aortic valve replacement (TAVR). However data on pre-existing cardiac implantable electronic devices (CIED) in TAVR patients has not been reported. We studied the impact of valve type and device type on mortality in those patients. Methods: We retrospectively reviewed patients with pre-existing CIEDs who underwent TAVR in a large hospital between 2012-2020. Valve types included self-expandable (SE) and balloon expandable (BE). For analysis, we grouped all ICD patients (ICD), dual chamber pacemakers (DPM) and single chamber pacemaker (SPM). Results: Of the total 111 patients studied, SPM included 12 (10.8%) patients, DPM 84 (75.7%) and ICD 15 (13.5%). SPM was associated with the highest mortality (HR 2.86, CI: 1.35-6.03, P= 0.0059) vs ICD (HR: 0.82, P= 0.64) vs DPM (HR 1, reference). SPM had the lowest median survival time of 15 months compared to DPM (53m) and ICD (60m), P=0.01 (Figure 1A). Based on valve type, 76 (67.3%) patients comprised the BE group vs 37 (32.7%) in the SE group. No difference in mortality was observed with valve type (BE, HR 1.3532, CI: 0.717- 2.555, P=0.351). Figure 1B Conclusion: Patients with SPM have the highest mortality with TAVR and valve type did not affect mortality in this population.




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