Acute Angioedema in a COVID-19 Positive Patient Requiring Intubation
A 78-year old woman with medical history significant for AF on anticoagulation, HTN, HLD, presented with 8 hour history of tongue and lip swelling. Two days prior, patient arrived with palpitations and shortness of breath. Testing was positive for COVID-19. She had no known allergies and received bamlanivimab and etesvimab infusions 12 hours prior to symptom onset. Patient was saturating well on room air but symptoms were refractory to steroids, diphenhydramine, and epinephrine. The decision was made to intubate for airway protection. With this case we will discuss the proposed pathophysiology involving COVID-19 associated angioedema and proposed management.
Ahmed R, Parry N, Soto RG. Acute angioedema in a COVID-19 positive patient requiring intubation. Paper presented at: The American Society of Anesthesiology Annual Meeting; 2021 Oct 8-12; San Diego, CA. Available at: https://www.abstractsonline.com/pp8/#!/9323/presentation/5291