The Impact of Diabetes Mellitus on Restenosis and Target Lesion Revascularization Following Percutaneous Coronary Intervention

Document Type

Conference Proceeding

Publication Date

5-2025

Publication Title

Journal of the Society for Cardiovascular Angiography and Interventions

Abstract

Background: Diabetes mellitus (DM) is a risk factor for adverse outcomes after percutaneous coronary intervention (PCI), such as restenosis and the need for target lesion revascularization (TLR). This study evaluates diabetes’ impact on clinical outcomes, focusing on restenosis and revascularization rates. Methods: We conducted a single-center, observational study analyzing patients undergoing PCI for acute coronary syndrome. Baseline characteristics were compared between patients with and without DM. Logistic regression assessed the relationship between DM and clinical outcomes at 30 days, 6 months, and 1 year. A p-value < 0.05 was considered significant. Results: Among 1,633 patients, 52.66% had DM. Diabetic patients were older (mean age 65.7 vs. 63.9 years, p < 0.001) and had higher rates of hypertension and chronic kidney disease. DM was linked to increased TLR risk at 6 months (odds ratio:1.83, p = 0.01) and higher rates of any lesion revascularization at 1 year (odds ratio: 1.54, p =0.004). No significant differences in 30-day mortality or recurrent acute coronary syndrome were observed. Conclusions: DM increases the risk of restenosis and TLR following PCI, especially in the medium to long term, underscoring the need for tailored strategies to improve outcomes in DM patients.

Volume

4

Issue

5 Suppl

First Page

46

Comments

Society for Cardiovascular Angiography and Interventions SCAI 48th Annual Scientific Sessions, May 1-3, 2025, Washington, DC

Last Page

47

DOI

10.1016/j.jscai.2025.103221

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