Re-irradiation of a Classic Kaposi's Sarcoma Using Volumetric Modulated Arc Therapy.
Document Type
Article
Publication Date
1-7-2024
Publication Title
Cureus
Abstract
A black male in his 60s diagnosed with classic Kaposi's sarcoma presented with multiple cutaneous nodules and edema of the right foot and lower leg. He was initially treated with alitretinoin 1% topical treatment. However, 16 months after treatment with the alitretinoin, the skin lesions progressed, and he subsequently underwent a course of radiation therapy to a total dose of 2000 centigrays (cGy) in five fractions to his right foot and lower extremities. Approximately 1.5 years after the radiation therapy was completed, multiple new lesions developed on the right foot and distal lower leg. He then underwent a course of re-irradiation to this area using volumetric modulated arc therapy (VMAT) to a total dose of 3300 cGy in 11 fractions. At a four-week follow-up visit, the skin lesions had completely resolved; however, the patient experienced mild edema and tenderness of the right foot and lower leg. Although long-term outcomes need to be followed, re-irradiation showed positive short-term outcomes for classic Kaposi's sarcoma.
Volume
16
Issue
1
First Page
e51782
Last Page
e51782
Recommended Citation
Chen Z, Daveluy S, Baran G, Joiner M, Miller S. Re-irradiation of a classic Kaposi's sarcoma using volumetric modulated arc therapy. Cureus. 2024 Jan 7;16(1):e51782. doi: 10.7759/cureus.51782. PMID: 38322087.
DOI
10.7759/cureus.51782
ISSN
2168-8184
PubMed ID
38322087