Langerhans Cell Histiocytosis of Vulva in a Pediatric Patient

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Authors

Sarah Pilarski, Michigan State University College of Human Medicine Medical Student
Kania McGhee, Corewell Health West
Kate Wiewiora, Corewell Health West Resident
Vyvian Borse-Hatchett, Corewell Health West Resident

Description

Langerhans Cell Histiocytosis (LCH) is a rare disorder characterized by proliferation of histiocytes in various tissues, most commonly affecting the bone and skin. Its clinical manifestations vary widely, ranging from local lesions to disseminated involvement. Patient presentations range from self-healing skin lesions to multi-organ dysfunction resistant to treatment. The unpredictable presentation of LCH can lead to diagnostic delay, particularly in pediatric patients with vulvar lesions at presentation. This case report highlights the significance of a proper gynecological evaluation in pediatric patients, including biopsy and specialist referral if the etiology remains unclear.

Publication Date

5-9-2025

Disciplines

Obstetrics and Gynecology

Recommended Citation

Pilarski A, McGhee K, Wiewiora K, Borse-Hatchett V. Langerhans cell histiocytosis of vulva in a pediatric patient. Presented at: Research Day Corewell Health West; 2025 May 9; Grand Rapids, MI.

Comments

2025 Research Day Corewell Health West, Grand Rapids, MI, May 9, 2025. Abstract 1764