Toxic Erythema of Chemotherapy in Enfortumab Vedotin Limited to the Lower Extremities: Another Form of Pseudocellulitis

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Authors

Karissa Libson, Corewell Health West Resident
Lily Kauffman
Kalyn Hoffman
Catherine Chung
Benjamin Kaffenberger

Description

Pseudocellulitis describes conditions which mimic cellulitis but is not caused by infection and is typically a sterile inflammatory process. Enfortumab vedotin (EV) is an antibody drug conjugate used as a second or third line therapy to treat urothelial carcinoma. Toxic erythema of chemotherapy is the umbrella term for cutaneous toxicities caused by chemotherapeutic agents. Adverse skin reactions have been reported in almost half of patients taking EV ranging from severe cutaneous adverse reactions (SCARs) due to idiosyncratic hypersensitivity reactions to toxic erythema of chemotherapy resulting from off-target direct cutaneous toxicity.

Publication Date

5-9-2025

Recommended Citation

Libson K, Kaufman L, Hoffman K, Chung C, Kaffenberger B. Toxic erythema of chemotherapy in enfortumab vedotin limited to the lower extremities: Another form of pseudocellulitis. Presented at: Research Day Corewell Health West; 2025 May 9; Grand Rapids, MI.

Comments

2025 Research Day Corewell Health West, Grand Rapids, MI, May 9, 2025. Abstract 1750