Pigmented Villonodular Synovitis with Atypical Presentation in the Foot: A Case Report

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Authors

Humza Bhatti, Michigan State University College of Human Medicine Medical Student
Hussein Hazime, Michigan State University College of Human Medicine Medical Student
Philip Nowicki, Corewell Health West

Description

Pigmented villonodular synovitis (PVNS), also known as tenosynovial giant cell tumor (TGCT), is a rare proliferative disease of the synovial tissue that most commonly affects large joints such as the knee, hip, and shoulder in young individuals.1,2 PVNS can broadly be categorized into two types: localized PVNS (LPVNS) and diffuse PVNS (DPVNS), with the localized form being a mass within the synovium and the diffuse form involving the entire synovium.2,3 This rare condition has an incidence rate of 1.8 per million and is often misdiagnosed as arthritic disease. Early diagnosis is crucial as PVNS is often aggressive, and recurrence rates in the diffuse type have been reported to be as high as 46%.

Publication Date

5-9-2025

Disciplines

Orthopedics

Recommended Citation

Bhatti H, Hazime H, Nowicki P. Pigmented villonodular synovitis with atypical presentation in the foot: A case report. Presented at: Research Day Corewell Health West; 2025 May 9; Grand Rapids, MI.

Comments

2025 Research Day Corewell Health West, Grand Rapids, MI, May 9, 2025. Abstract 1736