Case Report: Kell Antigen Alloimmunization in a Gestational Carrier After Embryo Transfer Following in Vitro Fertilization

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Authors

Hawraa Alsaedi, Michigan State University College of Human Medicine Medical Student
Melissa Schott, Western Michigan Homer Stryker MD School of Medicine Medical Student
Robin Strouse
Emma Giuliani, Corewell Health West
Marcos Cordoba Munoz, Corewell Health West
Mili Thakur
Valerie Shavell

Description

The Kell antigen group is a highly immunogenic set of red blood cell (RBC) antigens, similar to ABO and Rh, that can provoke the formation of alloantibodies when introduced into the immune system of individuals who lack these antigens. Kell alloimmunization can lead to severe complications such as transfusion reactions and hemolytic disease of the fetus and newborn (HDFN). This report presents a case of Kell antigen alloimmunization in a gestational carrier who achieved a successful pregnancy with a genetically unrelated euploid embryo after in vitro fertilization (IVF) and preimplantation genetic testing (PGT).

Publication Date

5-9-2025

Disciplines

Obstetrics and Gynecology

Recommended Citation

Schott M, Alsaedi H, Strouse R, Giuliani E, Cordoba Munoz M, Thakur M, Shavell V. Case report: kell antigen alloimmunization in a gestational carrier after embryo transfer following in vitro fertilization. Presented at: Research Day Corewell Health West; 2025 May 9; Grand Rapids, MI.

Comments

2025 Research Day Corewell Health West, Grand Rapids, MI, May 9, 2025. Abstract 1845