Racial Disparities in the Outcomes of Myocardial Infarction With Non-Obstructive Coronary Arteries: A Propensity-Scorematched Nationwide Analysis

Document Type

Conference Proceeding

Publication Date

5-2025

Publication Title

Journal of the Society for Cardiovascular Angiography and Interventions

Abstract

Background: Myocardial Infarction with Nonobstructive Coronary Arteries (MINOCA) is defined by myocardial infarction criteria with nonobstructive coronary arteries (< 50% stenosis) and no identifiable cause for the acute presentation. This study evaluates racial disparities in MINOCA outcomes. Methods: A retrospective analysis of the National Inpatient Sample database (2016-2021) identified MINOCA patients by race (White, Black, Hispanic, Asian/Pacific Islander (PI), Native American (NA)) using ICD-10-CM codes. Propensity score matching (PSM) and multivariate regression adjusted for confounders, with propensity scores based on variables like age, sex, race, comorbidities, and hospital factors. Generalized linear models with double robust methods and inverse probability weighting balanced groups. Results: In PSM data, inpatient mortality was highest in Asian/PI (3.89%) patients vs. White (2.76%), Black (2.13%), Hispanic (2.63%), NA (0.78%) patients. However, multivariate analysis found no significant racial differences in mortality. Black patients had increased odds of acute heart failure (HF) (aOR 1.18, p < 0.001) and acute kidney injury (AKI) (aOR 1.24, p < 0.001). Asian/PI patients had higher HF risk (aOR 1.24, p = 0.033), while White and Hispanic patients had lower odds of arrhythmias (aOR 0.69, p < 0.001 for both). Conclusions: While in-hospital mortality disparities were not significant, Black and Asian/PI patients had increased odds of HF, and Black patients had higher AKI risk.

Volume

4

Issue

5 Suppl

First Page

25

Comments

Society for Cardiovascular Angiography and Interventions SCAI 48th Annual Scientific Sessions, May 1-3, 2025, Washington, DC

Last Page

25

DOI

10.1016/j.jscai.2025.103431

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