Outcomes of Mental Health Disorders in Patients With Myocardial Infarction With Nonobstructive Coronary Arteries: A Propensity-Score Matched Nationwide Analysis
Document Type
Conference Proceeding
Publication Date
5-2025
Publication Title
Journal of the Society for Cardiovascular Angiography and Interventions
Abstract
Background: Myocardial Infarction with non-obstructive coronary Arteries (MINOCA) is defined by myocardial infarction criteria with < 50% stenosis and no clear cause. While mental health disorders are linked to cardiovascular risk, their impact on MINOCA outcomes is not well studied. Methods: We performed a retrospective analysis of the National Inpatient Sample (2016-2021) to identify MINOCA patients, classified by the presence of mental health disorders using ICD-10-CM codes. Propensity score matching and multivariate regression analysis controlled for confounders. Logistic regression analysis was used to estimate propensity scores for primary and secondary outcomes, accounting for factors such as age, sex, race, income, insurance, and comorbidities. Double robust methods and inverse probability weighting balanced cases and controls in generalized linear models. Results: Mental health disorders were associated with increased in-hospital mortality (2.26% vs 1.21%, p< 0.001), sudden cardiac arrest (1.51% vs 0.65%, p< 0.001), pulmonary embolism (1.54% vs 0.65%, p< 0.001), and acute kidney injury (25.45% vs 20.24%, p< 0.001). No significant differences were found in acute stroke, mechanical circulatory device use, or defibrillator need (p>0.05). Conclusions: Mental health disorders in MINOCA are associated with higher mortality, sudden cardiac arrest, pulmonary embolism, and acute kidney injury, but not with stroke or device utilization.
Volume
4
Issue
5 Suppl
First Page
46
Last Page
47
Recommended Citation
Alrayyashi M, Bahar AR, Kaur P, Bahar Y, Alkhas C, Alraies MC. Outcomes of mental health disorders in patients with myocardial infarction with nonobstructive coronary arteries: a propensity-score matched nationwide analysis. J Soc Cardiovasc Angiogr Interv. 2025 May;4(Suppl 5):46-47. doi:10.1016/j.jscai.2025.102962 External Link
DOI
10.1016/j.jscai.2025.102962 External Link
Comments
Society for Cardiovascular Angiography and Interventions SCAI 48th Annual Scientific Sessions, May 1-3, 2025, Washington, DC