Title

Prosthesis-Patient Mismatch After Aortic Valve Replacement in the PARTNER 2 Trial and Registry.

Document Type

Article

Publication Date

7-12-2021

Publication Title

JACC. Cardiovascular interventions

Abstract

OBJECTIVES: This study aimed to compare incidence and impact of measured prosthesis-patient mismatch (PPM

BACKGROUND: TAVR studies have used measured effective orifice area indexed (EOAi) to body surface area (BSA) to define PPM, but most SAVR series have used predicted EOAi. This difference may contribute to discrepancies in incidence and outcomes of PPM between series.

METHODS: The study analyzed SAVR patients from the PARTNER (Placement of Aortic Transcatheter Valves) 2A trial and TAVR patients from the PARTNER 2 SAPIEN 3 Intermediate Risk registry. PPM was classified as moderate if EOAi ≤0.85 cm

RESULTS: The incidence of moderate and severe PPM

CONCLUSIONS: EOAi measured by echocardiography results in a higher incidence of PPM following SAVR or TAVR than PPM based on predicted EOAi. Severe PPM

Volume

14

Issue

13

First Page

1466

Last Page

1477

DOI

10.1016/j.jcin.2021.03.069

ISSN

1876-7605

PubMed ID

34238557

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